This table resumes the total number of protease genes in the human,
mouse and rat genomes, including orthologous genes, and human-,
mouse- or rat-specific genes. Some functional genes have been
inactivated by deleterious mutations in one species, and they are
mentioned, although they are not included in the final count.
| Catalytic
class |
||||||
|---|---|---|---|---|---|---|
| Total | Aspartic | Cysteine | Metallo | Serine | Threonine | |
| Human proteases | 561 | 21 | 148 | 186 | 178 | 28 |
| Mouse proteases | 641 | 27 | 163 | 198 | 227 | 26 |
| Rat
proteases |
626 |
24 |
160 |
192 |
221 |
29 |
| Rat/human orthologs | 524 | 21 | 135 | 177 | 165 | 26 |
| Rat/mouse orthologs | 583 |
24 |
151 |
191 |
191 |
26 |
| Rat-specific | 42 |
0 | 9 |
1 |
29 | 3 |
| Rodent-specific | 62 |
3 |
16 |
15 | 28 |
0 |
| Human-specific | 31 |
0 |
11 |
9 |
9 |
2 |
| Human gene/rat pseudogene | 9 |
0 |
3 |
3 |
3 |
0 |
| Rat gene/human pseudogene | 21 |
1 |
1 |
7 |
12 |
0 |
| Mouse
gene/rat pseudogene |
12 |
1 |
2 |
4 |
5 |
0 |
| Rat
gene/mouse pseudogene |
1 |
0 |
1 |
0 |
0 |
0 |
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