Crecimiento y cáncer

Jefe de unidad

Fernando Santos Rodríguez

Ubicación

Facultad de Medicina. Área de Pediatría

 

 

Líneas de investigación

  • Modelos experimentales de hipocrecimiento secundario:
  • Administración de rapamicina
  • Depleción de Potasio
  • Crecimiento en insuficiencia renal crónica
  • Metabolismo mineral y ácido-base

 

Publicaciones seleccionadas

  • Carbajo E, López JM, Santos F, Ordóñez FA, Niño P, Rodríguez J: Histological and dynamic changes induced by chronic metabolic acidosis in the rat growth plate J Am Soc Nephrol 2001;12:1228-1234.
  • Fernández M, Medina A, Santos F, Carbajo E, Rodríguez J, Álvarez J, Cobo A: Exacerbated inflammatory response induced by insulin-like growth factor I treatment in rats with ischemic acute renal failure. J Am Soc Nephrol 2001;12: 1900-1907.
  • Ferrando S, Rodríguez J, Santos F, Weruaga A, Fernández M, Carbajo E, García E: Effects of growth hormone treatment on the pituitary expression of GHRH receptor mRNA in uremic rats. Kidney Int 2002;62:775-779.
  • Medina A, Fernández-Fuente M, Carbajo-Pérez E, Santos F, Amil B, Rodríguez J, Crespo M. “Insulin-like growth factor I administration in young rats with acute renal failure”. Pediatric Nephrology. 2002; 17: 1005-1012.
  • Amil B, Santos F, Ordoñez FA, Martínez V, Málaga S. “Severe acute abdominal pain in a patient with steroid-sensitive idiopathic nephrotic síndrome”. Pediatric Nephrology. 2002; 17: 875-876.
  • Ferrando S, Rodríguez J, Santos F, Weruaga A, Fernández M, Carbajo E, García E. “Effects of growth hormone treatment on the pituitay expression of GHRH receptor mRNA in uremic rats” Kidney International. 2002; 62: 775-779
  • Amil B, Fernández-Fuente M, Molinos I, Rodríguez J, Carbajo-Pérez E, García E, Yamamoto T, Santos F. “Chondromodulin-I expression in the growth plate young uremic rats”. Kidney International. 2004; 66: 51-59.
  • Fernández-Fuente M, Santos F, Carbajo-Pérez E, Rodríguez J; Weruaga A, Amil B, Molinos I, García E. “Growth plate height of uremic rats is influenced by severity and duration of renal failure”. Pediatric Nephrology. 2004; 19: 187-192.
  • Santos F, Carbajo-Pérez E, Rodríguez J, Fernández-Fuente M, Molinos I, Amil B, García E. “Alterations of the growth plate in chronic renal failure”. Pediatric Nephrology. 2005; 20: 330-334.
  • Molinos I, Santos F, Carbajo-Pérez E, García E, Rodríguez J, García-Álvarez O, Gil H, Ordoñez F.A, Loredo V, Mallada L. “Catch-up growth follows an abnormal pattern in experimental renal insufficiency and growth hormone treatment normalizes it”. Kidney international. 2006; 70: 1955-1961.
  • Álvarez-García O, Carbajo-Pérez E, García E, Gil H, Molinos I, Rodríguez J, Ordoñez F.A, Santos F. “Rapamycin retards growth and causes marked alterations in the growth plate of young rats”. Pediatric Nephrology. 2007; 22: 954-961.
  • Gil H, Santos F, García E, Álvarez MV, Ordoñez F.A, Málaga S, Coto E. “Distal RTA with nerve deafness: a clinical spectrum and mutational analisis in five children”. Pediatric Nephrology. 2007; 22: 825-828.
  • Álvarez-García O, García-López E, Rodríguez J, Gil-Peña H, Molinos I, Carbajo-Pérez E, Santos F. “Administration of ghrelin to young uraemic rats increases foof intake transiently, stimulates growth hormona secretion and does not improvide longitudinal growth”. Nephrology Dialysis Transplantation. 2007; 22: 1309-1313.