{"id":1511,"date":"2022-01-31T11:47:49","date_gmt":"2022-01-31T11:47:49","guid":{"rendered":"https:\/\/www.unioviedo.es\/IUOPA\/?page_id=1511"},"modified":"2023-06-19T12:56:06","modified_gmt":"2023-06-19T10:56:06","slug":"biosynthesis-of-anti-tumour-molecules","status":"publish","type":"page","link":"https:\/\/www.unioviedo.es\/IUOPA\/en\/research\/biosynthesis-of-anti-tumour-molecules\/","title":{"rendered":"Biosynthesis of Anti-Tumour Molecules"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: #f8f8f8;background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-center fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-1{margin-top:0px!important; margin-right:0px!important;margin-bottom:31px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-1{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"font-size:14px;margin-top:0px;margin-right:0px;margin-bottom:31px;margin-left:0px;\"><h2 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;font-size:1em;--fontSize:14;--minFontSize:14px;line-height:1.3;\"><p><strong>UNIT HEADS<\/strong><br \/>\nM\u00aa Carmen M\u00e9ndez Fern\u00e1ndez<br \/>\nCarlos Olano \u00c1lvarez<\/p>\n<p><strong>LOCATION<\/strong><br \/>\nDepartamento de Biolog\u00eda Funcional.\u00a0Area de Microbiolog\u00eda.<br \/>\nFacultad de Medicina.<br \/>\nC\/ Julian Claver\u00eda s\/n<br \/>\n33006, Oviedo<\/p><\/h2><\/div><div class=\"fusion-separator\" style=\"align-self: flex-start;margin-right:auto;margin-bottom:30px;width:100%;max-width:100px;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"border-color:#25afb4;border-top-width:2px;\"><\/div><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:7px;width:100%;\"><\/div><div class=\"fusion-text fusion-text-1\"><p><strong>RESEARCH LINES<\/strong><\/p>\n<p>Biosynthesis of Antitumor Molecules group (BMA) research lines of have as main objective the generation of novel derivatives of antitumor compounds.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-0{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-0 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-0{width:100% !important;order : 1;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 2.88%;margin-left : 2.88%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-0{width:100% !important;margin-bottom : 6%;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-center fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-1 hover-type-none\"><img decoding=\"async\" width=\"400\" height=\"320\" title=\"PIB-biosintesis\" src=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/PIB-biosintesis.png\" data-orig-src=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/PIB-biosintesis.png\" alt class=\"lazyload img-responsive wp-image-2783\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27400%27%20height%3D%27320%27%20viewBox%3D%270%200%20400%20320%27%3E%3Crect%20width%3D%27400%27%20height%3D%27320%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/PIB-biosintesis-200x160.png 200w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/PIB-biosintesis.png 400w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px\" \/><\/span><\/div><div class=\"fusion-separator\" style=\"align-self: flex-start;margin-right:auto;margin-bottom:120px;width:100%;max-width:100px;\"><\/div><div style=\"text-align:center;\"><style>.fusion-button.button-1{border-radius:0 0 0 0;}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-default button-1 fusion-button-default-span \" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/biomic.grupos.uniovi.es\/inicio\"><span class=\"fusion-button-text\">Lab web page<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-1{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-1 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-1{width:100% !important;order : 1;}.fusion-builder-column-1 > .fusion-column-wrapper {margin-right : 2.88%;margin-left : 2.88%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-1{width:100% !important;margin-bottom : 6%;}.fusion-builder-column-1 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-1{ padding-top : 70px;margin-top : 0px;padding-right : 30px;padding-bottom : 70px;margin-bottom : 0px;padding-left : 30px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: #ffffff;background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-center\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-2\"><p>Several techniques of genetic engineering are applied for this purpose to microorganism in order to identify, isolate and characterize gene clusters involved in the biosynthesis of antitumor compounds and their manipulation. This manipulation consist, in general terms, in genetic inactivation and the ectopic expression of genes from two or more biosynthesis gene clusters in the producer microorganism of an specific antitumor compound. The objective of those approaches, named Combinatorial Biosynthesis\u201d, is the generation of novel molecules with structural characteristics different from the original natural product, thus generating hybrid molecules.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-2{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-2 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-2{width:100% !important;order : 0;}.fusion-builder-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-2{width:100% !important;order : 0;}.fusion-builder-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-2 hover-type-none\"><img decoding=\"async\" width=\"448\" height=\"235\" title=\"BMA_Genome-mining-small-1\" src=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_Genome-mining-small-1.jpg\" data-orig-src=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_Genome-mining-small-1.jpg\" alt class=\"lazyload img-responsive wp-image-1161\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27448%27%20height%3D%27235%27%20viewBox%3D%270%200%20448%20235%27%3E%3Crect%20width%3D%27448%27%20height%3D%27235%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_Genome-mining-small-1-200x105.jpg 200w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_Genome-mining-small-1-400x210.jpg 400w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_Genome-mining-small-1.jpg 448w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 448px\" \/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-3{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-3 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-3{width:100% !important;order : 0;}.fusion-builder-column-3 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-3{width:100% !important;order : 0;}.fusion-builder-column-3 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-2{ padding-top : 70px;margin-top : 0px;padding-right : 30px;padding-bottom : 50px;margin-bottom : 0px;padding-left : 30px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: #ffffff;background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-center\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-3 hover-type-none\"><img decoding=\"async\" width=\"417\" height=\"412\" title=\"BMA_Mithraymcyin-small\" src=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_Mithraymcyin-small.jpg\" data-orig-src=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_Mithraymcyin-small.jpg\" alt class=\"lazyload img-responsive wp-image-1162\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27417%27%20height%3D%27412%27%20viewBox%3D%270%200%20417%20412%27%3E%3Crect%20width%3D%27417%27%20height%3D%27412%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_Mithraymcyin-small-200x198.jpg 200w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_Mithraymcyin-small-400x395.jpg 400w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_Mithraymcyin-small.jpg 417w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 417px\" \/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-4{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-4 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-4{width:100% !important;order : 0;}.fusion-builder-column-4 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-4{width:100% !important;order : 0;}.fusion-builder-column-4 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-5 fusion_builder_column_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-3\"><p>In the present we are also focusing our attention in the identification and isolation of novel antitumor compounds produced by actinomycetes isolated from leaf-cutting ants from Peru. In this research line we are sequencing genomes of these actinomycetes in order to identify silent clusters, in standard culture laboratory conditions, which will be then activated using genetic engineering. The selection of these silent clusters will be based in the analysis of the novelty of the deduced structural characteristics of each compound determined by bioinformatics analysis.<\/p>\n<\/div><div class=\"fusion-text fusion-text-4\"><p>Furthermore, we are also interested on the study of metabolic pathways and regulatory mechanisms involved in the biosynthesis of antitumor compounds in order to improve the production of the novel antitumor derivatives generated.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-5{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-5 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-5{width:100% !important;order : 0;}.fusion-builder-column-5 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-5{width:100% !important;order : 0;}.fusion-builder-column-5 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-3{ padding-top : 10px;margin-top : 0px;padding-right : 30px;padding-bottom : 10px;margin-bottom : 0px;padding-left : 30px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-4 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: #ffffff;background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-center\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-6 fusion_builder_column_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-5\"><p><strong>Research lines:<\/strong><\/p>\n<p>\u2022 Characterization of antitumor compounds biosynthesis pathways.<br \/>\n\u2022 Generation of novel antitumor compounds by combinatorial biosynthesis.<br \/>\n\u2022 Production improvement of antitumor compounds.<br \/>\n\u2022 Metabolic engineering of biosynthesis pathways.<br \/>\n\u2022 Genome mining to activate silent pathways for the discovery of novel antitumor compounds.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-6{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-6 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-6{width:100% !important;order : 0;}.fusion-builder-column-6 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-6{width:100% !important;order : 0;}.fusion-builder-column-6 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-7 fusion_builder_column_1_2 1_2 fusion-flex-column fusion-flex-align-self-center\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-4 hover-type-none\"><img decoding=\"async\" width=\"448\" height=\"336\" title=\"OLYMPUS DIGITAL CAMERA\" src=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_l1-1.jpg-1.jpg\" data-orig-src=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_l1-1.jpg-1.jpg\" alt class=\"lazyload img-responsive wp-image-1165\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27448%27%20height%3D%27336%27%20viewBox%3D%270%200%20448%20336%27%3E%3Crect%20width%3D%27448%27%20height%3D%27336%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_l1-1.jpg-1-200x150.jpg 200w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_l1-1.jpg-1-400x300.jpg 400w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2022\/01\/BMA_l1-1.jpg-1.jpg 448w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 448px\" \/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-7{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-7 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-7{width:100% !important;order : 0;}.fusion-builder-column-7 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-7{width:100% !important;order : 0;}.fusion-builder-column-7 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-4{ padding-top : 50px;margin-top : 0px;padding-right : 30px;padding-bottom : 50px;margin-bottom : 0px;padding-left : 30px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-5 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: #f8f8f8;background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-8 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-6\"><p><strong>GROUP HEAD BIOGRAPHY<\/strong><\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-8{width:100% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-8 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-8{width:100% !important;order : 0;}.fusion-builder-column-8 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-8{width:100% !important;order : 0;}.fusion-builder-column-8 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-9 fusion_builder_column_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;border-width: 0 2px 0 0;border-color:#76b5ae;border-style:solid;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-7\"><p><b>Carmen M\u00e9ndez<\/b>\u00a0graduated from the University of Oviedo, Spain, in 1984 with a Ph.D. based on the characterization of events that take place during the differentiation processes of colonies of Streptomyces antibioticus. After a post-doctoral stay in Keith Chater\u2019s laboratory in Norwich, UK, she returned to Oviedo, Spain, where she became Associate Professor in Microbiology in 1988. Since 2011 she has been a Full Professor of Microbiology at the University of Oviedo. Her major interests are the cloning and characterization of biosynthetic pathways of antibiotics and antitumor compounds in actinomycetes, the generation of novel compounds with potential antibiotic or antitumor activities through combinatorial biosynthesis, and the activation of silent pathways in actinomycetes.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-9{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-9 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-9{width:100% !important;order : 0;}.fusion-builder-column-9 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-9{width:100% !important;order : 0;}.fusion-builder-column-9 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-10 fusion_builder_column_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-8\"><p><b>Carlos Olano g<\/b>raduate in Biology (1991), PhD in Biology and Extraordinary PhD Thesis Award (1995) by the University of Oviedo (Spain). After a postdoctoral period at the School of Pharmacy, University of Wisconsin (Madison, WI, USA), reincorporates at the University of Oviedo as research assistant of the University Institute of Oncology from Principado de Asturias (IUOPA). Later he got a position as Associate Professor at the University of Oviedo and Professor at 2021. He forms part, from the beginning, of the University of Oviedo research team \u201cBiosynthesis of bioactive compounds by microorganisms (BIOMIC)\u201d. C. Olano present research interests are: identification of novel secondary metabolism pathways using genome mining; identification of novel bioactive compounds; isolation and characterization of novel biosynthesis gene clusters \u00a0(BGC) \u00a0leading to novel bioactive compounds; use of combinatorial biosynthesis to generate novel derivatives; and the activation of cryptic\/silent BGCs using genetic engineering approaches.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-10{width:50% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-10 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-10{width:100% !important;order : 0;}.fusion-builder-column-10 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-10{width:100% !important;order : 0;}.fusion-builder-column-10 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-5{ padding-top : 70px;margin-top : 0px;padding-right : 30px;padding-bottom : 70px;margin-bottom : 0px;padding-left : 30px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-6 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: #ffffff;background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-11 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-9\"><p><strong>SELECTED PUBLICATIONS<\/strong><\/p>\n<ul>\n<li>Prado-Alonso L, P\u00e9rez-Victoria I, Malmierca MG, Montero I, Rioja-Blanco E, Mart\u00edn J, Reyes F, M\u00e9ndez C, Salas JA, Olano C. (2022).\u00a0 Colibrimycins, Novel Halogenated Hybrid Polyketide Synthase-Nonribosomal Peptide Synthetase (PKS-NRPS) Compounds Produced by\u00a0<em>Streptomyces<\/em>\u00a0sp. Strain CS147. Appl Environ Microbiol. 88(1): e0183921.<\/li>\n<li>Ceniceros A, Cuervo L, M\u00e9ndez C, Salas JA, Olano C, Malmierca MG. (2021).\u00a0 A Multidisciplinary Approach to Unraveling the Natural Product Biosynthetic Potential of a\u00a0<em>Streptomyces<\/em>\u00a0Strain Collection Isolated from Leaf-Cutting Ants. Microorganisms. 9(11): 2225.<\/li>\n<li>Botas A, Eitel M, Schwarz PN, Buchmann A, Costales P, N\u00fa\u00f1ez LE, Cort\u00e9s J, Mor\u00eds F, Krawiec M, Wola\u0144ski M, Gust B, Rodriguez M, Fischer WN, Jandeleit B, Zakrzewska-Czerwi\u0144ska J, Wohlleben W, Stegmann E, Koch P, M\u00e9ndez C, Gross H. (2021). Genetic Engineering in Combination with Semi-Synthesis Leads to a New Route for Gram-Scale Production of the Immunosuppressive Natural Product Brasilicardin\u2005A. Angew Chem Int Ed Engl. 60(24): 13536-13541.<\/li>\n<\/ul>\n<ul>\n<li>Malmierca MG, P\u00e9rez-Victoria I, Mart\u00edn J, Reyes F, M\u00e9ndez C, Salas JA, Olano C. (2020). New Sipanmycin Analogues Generated by Combinatorial Biosynthesis and Mutasynthesis Approaches Relying on the Substrate Flexibility of Key Enzymes in the Biosynthetic Pathway. Applied and Environmental Microbiology 86(3):e02453-19.<\/li>\n<li>Becerril A, Perez-Victoria I, Ye S, Brana AF, Martin J, Reyes F, Salas JA, Mendez C. (2020). Discovery of Cryptic Largimycins in Streptomyces Reveals Novel Biosynthetic Avenues Enriching the Structural Diversity of the Leinamycin Family. ACS Chemical Biology 15 (6): 1541-1553.<\/li>\n<li>Zabala D, Song LJ, Dashti Y, Challis GL, Salas JA, Mendez C. (2020). Heterologous reconstitution of the biosynthesis pathway for 4-demethyl-premithramycinone, the aglycon of antitumor polyketide mithramycin. Microbial Cell Factories 19(1). 111.<\/li>\n<li>Becerril A, \u00c1lvarez S, Bra\u00f1a AF, Rico S, D\u00edaz M, Santamar\u00eda RI, Salas JA, M\u00e9ndez C. (2018). Uncovering production of specialized metabolites by <em>Streptomyces argillaceus<\/em>: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches. PLoS One. 24;13(5):e0198145.<\/li>\n<li>Ye S, Bra\u00f1a AF, Gonz\u00e1lez-Sab\u00edn J, Moris JF, Olano C, Salas JA, M\u00e9ndez C. (2018). New insights into the biosynthesis pathway of polyketide alkaloid argimycins P in <em>Streptomyces argillaceus<\/em>. Frontiers in Microbiology 9:252.<\/li>\n<li>Malmierca MG, P\u00e9rez-Victoria I, Mart\u00edn J, Reyes F, M\u00e9ndez C, Olano C, Salas JA. (2018). Cooperative involvement of glycosyltransferases in the transfer of aminosugars in the biosynthesis of the macrolactam sipanmycin by <em>Streptomyces<\/em> sp. CS149. Applied and Environmental Microbiology 84 (18) e01462-18.<\/li>\n<\/ul>\n<ul>\n<li>N\u00fa\u00f1ez LE, Nybo SE, Gonz\u00e1lez-Sab\u00edn J, P\u00e9rez M, Men\u00e9ndez N, Bra\u00f1a AF, Shaaban KA, He M, Mor\u00eds F, Salas JA, Rohr J, M\u00e9ndez C. (2012). A novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis. J Med Chem. 55(12):5813-25.<\/li>\n<\/ul>\n<\/div><div ><span class=\" fusion-imageframe imageframe-none imageframe-5 hover-type-none\"><img decoding=\"async\" width=\"900\" height=\"596\" title=\"biosintesisTeam\" src=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/biosintesisTeam.jpg\" data-orig-src=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/biosintesisTeam.jpg\" alt class=\"lazyload img-responsive wp-image-2666\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27900%27%20height%3D%27596%27%20viewBox%3D%270%200%20900%20596%27%3E%3Crect%20width%3D%27900%27%20height%3D%27596%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/biosintesisTeam-200x132.jpg 200w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/biosintesisTeam-400x265.jpg 400w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/biosintesisTeam-600x397.jpg 600w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/biosintesisTeam-800x530.jpg 800w, https:\/\/www.unioviedo.es\/IUOPA\/wp-content\/uploads\/2023\/06\/biosintesisTeam.jpg 900w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 900px\" \/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-11{width:100% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-11 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-11{width:100% !important;order : 0;}.fusion-builder-column-11 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-11{width:100% !important;order : 0;}.fusion-builder-column-11 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-6{ padding-top : 70px;margin-top : 0px;padding-right : 30px;padding-bottom : 70px;margin-bottom : 0px;padding-left : 30px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-7 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-12 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-blend-mode: overlay;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-section-separator section-separator triangle fusion-section-separator-1\"><div class=\"fusion-section-separator-svg\" style=\"border-bottom:1px solid #f8f8f8;\"><div class=\"divider-candy-arrow bottom\" style=\"top:0px;border-top-color: #f8f8f8;\"><\/div><div class=\"divider-candy bottom\" style=\"bottom:-21px;border-bottom:1px solid #f8f8f8;border-left:1px solid #f8f8f8;\"><\/div><\/div><div class=\"fusion-section-separator-spacer\"><div class=\"fusion-section-separator-spacer-height\" style=\"height:1px;\"><\/div><\/div><style type=\"text\/css\">.fusion-section-separator-1 .fusion-section-separator-svg {margin-left:1.92%;margin-right:1.92%;}@media only screen and (max-width:1024px) {.fusion-section-separator-1 .fusion-section-separator-svg {margin-left:1.92%;margin-right:1.92%;}}@media only screen and (max-width:640px) {.fusion-section-separator-1 .fusion-section-separator-svg {margin-left:1.92%;margin-right:1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-12{width:100% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-12 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-12{width:100% !important;}.fusion-builder-column-12 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-12{width:100% !important;}.fusion-builder-column-12 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-7{ padding-top : 0px;margin-top : 0px;padding-right : 30px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 30px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-8 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: #e8e8e8;background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-center\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-13 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-2{margin-top:0px!important; margin-right:0px!important;margin-bottom:31px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-2{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-2 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-two\" style=\"font-size:60px;margin-top:0px;margin-right:0px;margin-bottom:31px;margin-left:0px;\"><h2 class=\"title-heading-center fusion-responsive-typography-calculated\" style=\"margin:0;font-size:1em;color:#ffffff;--fontSize:60;line-height:1.3;\">Personnel<\/h2><\/div><div class=\"fusion-separator\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-bottom:30px;width:100%;max-width:100px;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"border-color:#ffffff;border-top-width:2px;\"><\/div><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:20px;width:100%;\"><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-13{width:100% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-13 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-13{width:100% !important;}.fusion-builder-column-13 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-13{width:100% !important;}.fusion-builder-column-13 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-14 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-10\"><table width=\"100%\">\n<tbody>\n<tr>\n<td width=\"179\"><strong>Name<\/strong><\/td>\n<td width=\"108\"><strong>Position<\/strong><\/td>\n<td width=\"252\"><strong>E-mail<\/strong><\/td>\n<td width=\"80\"><strong>Phone<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"179\"><b>Carmen M\u00e9ndez Fern\u00e1ndez<\/b><\/td>\n<td width=\"108\">Group leader<\/td>\n<td width=\"252\"><a href=\"mailto:cmendezf@uniovi.es\">cmendezf@uniovi.es<\/a><\/td>\n<td width=\"80\">985 103 558<\/td>\n<\/tr>\n<tr>\n<td width=\"179\"><b>Carlos Olano \u00c1lvarez<\/b><\/td>\n<td width=\"108\">Group leader<\/td>\n<td width=\"252\"><a href=\"mailto:olanocarlos@uniovi.es\">olanocarlos@uniovi.es<\/a><\/td>\n<td width=\"80\">985 105 288<\/td>\n<\/tr>\n<tr>\n<td width=\"179\">Gloria Blanco Blanco<\/td>\n<td width=\"108\">Staff scientist<\/td>\n<td width=\"252\"><a href=\"mailto:gbb@uniovi.es\">gbb@uniovi.es<\/a><\/td>\n<td width=\"80\">985 103 205<\/td>\n<\/tr>\n<tr>\n<td width=\"179\">M\u00f3nica G\u00f3mez Malmierca<\/td>\n<td width=\"108\">Postdoctoral fellow<\/td>\n<td width=\"252\"><a href=\"mailto:gomezmonica@uniovi.es\">gomezmonica@uniovi.es<\/a><\/td>\n<td width=\"80\">985 105 288<\/td>\n<\/tr>\n<tr>\n<td width=\"179\">Lorena Cuervo del Pozo<\/td>\n<td width=\"108\"><\/td>\n<td width=\"252\"><a href=\"mailto:cuervolorena@uniovi.es\">cuervolorena@uniovi.es<\/a><\/td>\n<td width=\"80\">985 105 288<\/td>\n<\/tr>\n<tr>\n<td width=\"179\">Miriam Rodr\u00edguez Garc\u00eda<\/td>\n<td width=\"108\">Postdoctoral fellow<\/td>\n<td width=\"252\"><a href=\"mailto:miroga03@hotmail.com\">miroga03@hotmail.com<\/a><\/td>\n<td width=\"80\">985 105 287<\/td>\n<\/tr>\n<tr>\n<td width=\"179\">Laura Prado Alonso<\/td>\n<td width=\"108\">Predoctoral fellow<\/td>\n<td width=\"252\"><a href=\"mailto:laura-prado@outlook.com\">laura-prado@outlook.com<\/a><\/td>\n<td width=\"80\">985 105 288<\/td>\n<\/tr>\n<tr>\n<td width=\"179\">Coral Garc\u00eda Guti\u00e9rrez<\/td>\n<td width=\"108\">Predoctoral fellow<\/td>\n<td width=\"252\"><a href=\"mailto:coral93@hotmail.es\">coral93@hotmail.es<\/a><\/td>\n<td width=\"80\">985 105 287<\/td>\n<\/tr>\n<tr>\n<td width=\"179\">Mar\u00eda Soledad Gonz\u00e1lez Moreno<\/td>\n<td width=\"108\">Predoctoral fellow<\/td>\n<td width=\"252\"><a href=\"mailto:msol95gm@gmail.com\">msol95gm@gmail.com<\/a><\/td>\n<td width=\"80\">985 105 287<\/td>\n<\/tr>\n<tr>\n<td width=\"179\">Leire Pe\u00f1a Noval<\/td>\n<td width=\"108\">Technician<\/td>\n<td width=\"252\"><a href=\"mailto:penaleire@uniovi.es\">penaleire@uniovi.es<\/a><\/td>\n<td width=\"80\">985 105 287<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-14{width:100% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-14 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) 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