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Esther Alcorta
  • PI: Dra. Esther Alcorta
  • Faculty of Medicine. University of Oviedo
  • C/ Julián Clavería s/n , 33006 OVIEDO, SPAIN

Our lab is interested in the mechanisms of reception, transduction and coding of olfactory information and their translation into olfactory perception using a multidisciplinary approach.

We use Drosophila melanogaster as the model species because of the genetic tools that allow us to study, in complete alive animals, the functional consequences that directed expression changes of particular genes have at different levels (receptor neurons, olfactory receptor organs or complete individuals).

Thus, gene expression changes in the olfactory receptor organs, antennae and maxillary palps, (shown by RT-PCR, qRT-PCR, microarray analysis and immunohistochemistry) could be correlated to changes produced in the olfactory response of receptor neurons (measured by single sensila recording, SSR), receptor organs (measured by electroantennograms, EAGs) and in the behavioral responses of complete individuals.

From a more general view, the system could be used as a model to understand olfaction in different species, including invertebrates as well as vertebrates, and other sensory modalities.

Foto 1 Foto 2
Single Sensila Recording(SSR)
Y Maze

Last version, April 2017

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